摘要
实验观察了冷习服及性别对大鼠重度冻伤的影响。重度冻伤后，冷习服（ＣＡ）大鼠冻足组织存活面积（ＴＳＡ）较未冷习服（ＮＣＡ）大鼠冻足ＴＳＡ明显增高（Ｐ＜０．０１），雄、雌大鼠皆如此。不论冷习服与否，雌鼠冻足的ＴＳＡ均高于相应雄鼠冻足的ＴＳＡ，即大鼠抗冻能力存在着性别差异。这种差异还表现为ＮＣＡ和ＣＡ雌鼠冻足与未冻足皮肤温度差（ΔＴｓ）分别高于ＮＣＡ和ＣＡ雄鼠ΔＴｓ。ΔＴｓ增高间接反映了冻区血液循环较好，这是冻足组织损伤较轻的原因之一。上述结果表明，冷习服锻炼是减轻重度冻伤损伤的简单有效方法。在研究冷冻损伤的实验中，应排除性别差异的影响。
ffects of cold-acclimation and severe frostbite in Wistar rats were investigated. The experi-mental result shows that the tissue survival area(TSA)of frostbitten feet of cold-acclimated (CA) rats is higher than that of non cold-acclimated(NCA)rats obviously. Such a situation is in both sexes,whichsuggests that cold-acclimation training lower the extent of tissue after severe frostbite. Whethercold-acclimated or not,the TSA of female rats is better than that of male rats respectively. It indicates that there is a sexual difference in frostbite resistance of rats。It exists between skin temperatures of frost-bitten and unfrostbitten feet (ΔTs)too. The ΔTs of CA and NCA female rats is higher than that of CA and NCA male rats post-frostbite respectively. The increase of ΔTs of frostbitten feet of rats indicates indi-rectly the better bood circulation in frostbitten area,which might be one of the reasons for frostbitten feetto decrease the tissue damage. So we consider that cold-acclimation training is a simple and effectivemethod to lower the extent of severe cold injury and that the sex of rats shorld be same in experimentalresearch of cold injury in order to rule out the possibility of sexual difference.Effects of sex hormone oncold resistance and stress remain further research。
出处
《解放军预防医学杂志》
CAS
北大核心
1996年第5期324-326,共3页
Journal of Preventive Medicine of Chinese People's Liberation Army
关键词
冷习服
冻足
皮肤温度
cold-acclimation,tissue survival area of frostbitten feet,skin temperature of frostbitten feet, rat,sex
