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Rho/Rock信号通路在肾间质纤维化中的作用 被引量:1

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作者 付平 黄颂敏
出处 《中国中西医结合肾病杂志》 2006年第11期667-670,共4页 Chinese Journal of Integrated Traditional and Western Nephrology
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参考文献25

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二级参考文献34

  • 1姚建,黎磊石,周虹.大黄素对培养人系膜细胞纤维连接蛋白产生的抑制作用[J].肾脏病与透析肾移植杂志,1994,3(5):349-352. 被引量:26
  • 2Allison E. Basic science review: molecular basis of renal fibrosis.Pediatric Nephrol, 2000, 15: 290-301.
  • 3Nagatoya K, Moriyama T, Kawada N, et al. Y-27632 prevents tubulointerstitial fibrosis in mouse kidneys with unilateral ureteral obstruction. Kidney Int, 2002, 61: 1684-1695.
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  • 6Murata T, Arii S, Nakamura T, et al. Inhibitory effect of Y-27632, a ROCK inhibitor, on progression of rat liver fibrosis in association with inactivation of hepatic stellate cells. J Hepatol,2001,35:474-481.
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共引文献26

同被引文献15

  • 1王玉珍,姜慧卿,扈彩霞,吕晓萍,王丽娜,甄承恩.RhoA和肌球蛋白轻链在肝纤维化大鼠肝组织中的表达[J].基础医学与临床,2007,27(3):275-278. 被引量:6
  • 2KUROKAWA K, ITOH R E, YOSHIZAKI H, et al. Coactivation of Racl and Cdc42 at lamellipodia and membrane ruffles induced by epi- dermal growth factor [J] . Mol Biol Cell, 2004, 15 (3) : 1003 - 1010.
  • 3JI H, MENG Y, ZHANG X, et al. Aldosterone induction of hepatic stellate cell contraction through activation of RhoA/ROCK-2 signaling pathway [J] . Regul Pept, 2011, 169 (1 :3): 13-20.
  • 4VIATOUR P, MERVILLE MP, BOURS V, et al. Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflam- mation [J] . Trends Biochem Sci, 2005, 30 (1): 43-52.
  • 5RODRIGUEZ PL, SAHAY S, OLABISI OO, et al. ROCK I -media- ted activation of NF-kappaB by RhoB [J] . Cell Signal, 2007, 19 (11) : 2361 -2369.
  • 6HAMEL B, MONAGHAN-BENSON E, ROJAS R J, et al. SmgGDS isa guanine nucleotide exchange factor that specifically activates RhoA and RhoC [J] . J Biol Chem, 2011, 286 (14) : 12141 -12148.
  • 7DIEZ-FREIRE C, VAZQUEZ J, CORREA DAM, et al. ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR [J] . Physiol Genomics, 2006, 27 (1) : 12 -19.
  • 8HUENTELMAN MJ, GROBE JL, VAZQUEZ J, et al. Protection from angiotensin H-induced cardiac hypertrophy and fibrosis by sys- temic lentiviral delivery of ACE2 in rats [ J ] . Exp Physiol, 2005, 90 (5): 783-790.
  • 9VAN GOLEN KL, BAO L , DIVITO MM, et al. Reversion of RhoCGTPase-indueed ilu"lammatory breast cancer phenotype by treatment with a famesyl transferase inhibitor [J] . Mol Cancer Ther, 2002, 1 (8) : 575 -583.
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