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新诊断的2型糖尿病短期胰岛素强化治疗的临床观察

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摘要 目的:观察短期胰岛素强化治疗,对新诊断的2型糖尿病患者的降糖疗效及胰岛β细胞功能改善和长期血糖控制的影响。方法:采用自身前后对照,对18例新诊断的2型糖尿病患者,每日4次胰岛素强化治疗2个月,随诊1年。监测空腹血糖、三餐后2h血糖、糖化血红蛋白的前后变化。结果:所有患者治疗后空腹血糖、三餐后2h血糖、糖化血红蛋白迅速达到良好水平,较治疗前有显著差异性(P<0.01),1年后,14例患者仅需饮食控制,即可使血糖维持良好水平,4例患者需口服降糖药物。结论:新诊断的2型糖尿病患者应用短期胰岛素强化治疗,可快速控制血糖,改善β细胞功能,使其自然病程回到更早阶段,为长期控制血糖奠定了基础。
出处 《内蒙古医学杂志》 2006年第10期929-930,共2页 Inner Mongolia Medical Journal
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  • 1Weyer. Dificiency in AIR predict IGT and Type 2 diabetes. Diabetes Care, 2001,24 : 89-94.
  • 2Haffner SM, Miettinen H, Gaskill SP, et al. Decreased insulin secretion and increased insulin resistance are independently related to the 7-year risk of NIDDM in Mexican-Americans. Diabetes, 1995,44: 1386-1391.
  • 3Bruce DG, Chisholm DJ, Leonare H, et al. Physiological importance of deficiency in early prandial insulin secretion in non-in-sulin-dependent diabetes. Diabetes, 1988,37: 736-743.
  • 4Bruttomesso D, Pianta A, Mari A, et al. Restoration of early rise in plasma insulin levels improves the glucose tolerance of type 2 diabetic patients. Diabetes, 1999,48: 99-105.
  • 5Ilkova H, glaser B, Tunckale A, et al. Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment. Diabetes Care, 1997,20:1353-1356.
  • 6Walton C, Godsland IF, Proudler AJ, et al. Effect of body mass index and fat distribution on insulin sensitivity, secretion, and clearance in nonobese healthy men. J Clin Endocrinol Metab,1992,75: 170-175.
  • 7Purrello F, Rabuazza AM. Metabolic factors that affect betacell function and survival. Diabet Nutr Metab, 2000, 13: 84-91.
  • 8Sivitz WI. Lipotoxieity and glueotoxieity in type 2 diabetes. Effects on development and progression. Postgrad Med, 2001,109: 55-59,63-64.
  • 9Lenhard M J, Reeves GD. Continous subcutaneous insulin infusion: a comprehensive review of insulin pump therapy. Arch Intern Med,2001,161: 2293-2300.
  • 10Dupuy O, Mayaudon H, Palou M, et al. Optimized transient insulin infusion in uneontrolled type 2 Diabetes : Evaluation of a pragmatie attitude. Diabet Med, 2000,26 : 371-375.

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