摘要
目的:探讨短期胰岛素强化控制应激性高血糖对危重症临床疗效及预后的影响。方法:将172例合并应激性高血糖危重病患者随机分成胰岛素强化治疗组(治疗组)与常规胰岛素治疗组(对照组),对照组当血糖>11.9 mmol/L时,使用胰岛素将血糖控制在10～11.1 mmol/L;治疗组当血糖>6.1 mmol/L,使用胰岛素将血糖控制在4.0～6.1 mmol/L。强化治疗期为7天,7天后血糖控制及其处理均同对照组。结果:治疗组院感发生率、MODS发生率、死亡率较对照组明显降低;ICU住院时间较对照组明显缩短。结论:短期胰岛素强化治疗能有效提高危重症的治愈率,减少危重症并发症的发生,降低危重症的死亡率,并能缩短ICU住院时间,降低医疗费用。
Objective: To explore the effect of short term intensive insulin therapy on stress-induced hyperglycemia in serious patients. Methods: 172 serious patients with stress-induced hyperglycemia were randomly divided into short term intensive insulin therapy group (n=86) and normal therapy group (n=86). Patients in intensive insulin therapy group received insulin when their glycemia were above 6.1 mmol/L to maintain their giycemia in 4.0～6.1 mmol/L, Patients in normal therapy group received insulin when their glycemia were above 11.9 mmol/L to maintain their glycemia in 10.0～11.1 mmol/L after seven days, the results were observed. Results: Occurrence rate of hospital infecting, MODS and death rate were lower and time of ICU was shorter in intensive insulin therapy group than in normal therapy group. Conclusions: Short term intensive insulin therapy can increase the curing rate, reduce the side effect occurrence rate and death rate.
出处
《岭南急诊医学杂志》
2009年第2期115-116,共2页
Lingnan Journal of Emergency Medicine
关键词
危重症
应激性高血糖
胰岛素强化治疗
serious patients
stress-induced hyperglycemia
intensive insulin therapy
