摘要
ＮＤＶ腹腔免疫小鼠后３ｈ血浆ＡＣＴＨ水平升至高峰，６ｈ有所下降，１２ｈ基本恢复至正常水平；ＮＤＶ免疫后血浆皮质酮（ＣＳ）６ｈ升至高峰，１２ｈ已有大幅度下降，２４ｈ后基本恢复至正常水平。ＮＤＶ也可使大鼠血浆ＡＣＴＨ和ＣＳ水平增加。白喉类毒素足垫皮下免疫后小鼠血浆ＣＳ水平有类似变化。白喉类毒素和绵羊红细胞（ＳＲＢＣ）免疫后７天均可升高小鼠血浆ＣＳ水平；ＮＤＶ免疫后７天则可降低小鼠血浆ＣＳ水平。
Swiss mice were immunized with Newcastle disease virus(NDV),0.2ml (800HAU/ml) per mouse intraperitonelly, 3 hours later, plasma ACTH (Adrenocorticotropic hormone, ACTH) level was increased to the peak, and plasma ACTH Ievel was decreased to normal 12 hours after immunization; mouse plasma corticosterone level was increased to the peak 6 hours after DNV immunization. NDV also had the effect for increasing plasma ACTH and corticosterone in Wistar rats. Mouse plasma corticosterone levels were increased by SRBC(10%SRBC,0.2ml/per mouse i.p.)and toxoid diphtheria (10Lf/per back foot, for both side S.C.)but decreased by NDV 7 days after immunization.
出处
《汕头大学医学院学报》
1996年第1期1-3,共3页
Journal of Shantou University Medical College
