摘要
以Tween80为表面活性剂,正丁醇为助表面活性剂,通过绘制拟三元相图对食品级VE的O/W型微乳液配方和工艺进行了研究。结果表明:最佳条件为:在35℃下,Tween80:正丁醇=1∶1;VE:SAA:水为1∶99∶900。温度对微乳区域影响的考察发现随温度升高微乳区面积减小;通过分析电导率随组分变化的曲线划分出不同微乳类型区;用动态光散射法测定VE微乳液粒径大小一个月内的变化情况,表明VE微乳液稳定且平均粒径小于10nm;以正己烷为透析液,在25℃下,利用渗析—紫外分光光度法测定样本的释药率,显示48h后VE的包封率高达83.7%,具有明显的缓释作用。
The formulation and process of food-grade vitamin E microemulsion were studied by using Tween80 as surfactant, n-Butylalcohol as cosurfactant. Based on the test results, the optimal condition was as follows： Tween80 ： n-Butylalcohol = 1 ： 1 , the proportion of vitamin E ： SAA ： water was 1：99 ：900 at 35℃. Influence of temperature on the microemulsion region was determined with ternary diagrams. With the temperature increasing, the area of microcmulsion decreased. The O/W, W/O and B. C. regions were divided by conductance method. The changes of diameter of microemulsion in a month were measured by Dynamic Light Scattering in O/W region and the results showed that it was stable and the particle radius was less than 10 nm. Release rate of vitamin E against hexane was measured with dialysis-Uhraviolet Spectrophotometer. The resuhs revealed that the vitamin E envelopment was reached at 83.7% after 48 h, bearing remarkable release efficiency.
出处
《食品与机械》
CSCD
北大核心
2006年第5期36-39,共4页
Food and Machinery
基金
国家自然科学基金项目(项目编号:20473034)
江南大学"太湖学者"(2003)专项基金
教育部重点实验室开放课题(项目编号:KLIB-KF200504)
关键词
微乳液
VE
相图
缓释
Microemulsion
VE
Phase diagrams
Release
