摘要
测定了20例充血性心力衰竭患者洋地黄治疗时的运动耐力,同时用侵入性方法测定其心指数及肺小动脉嵌压。其后改服国产氨利酮15天,重复测定上述指标。结果表明:患者运动耐受时间较用地高辛时明显延长;基础心指数及肺小动脉嵌压与运动耐受时间之间及用氨利酮后上述指标的增值之间缺乏相关性。提示国产氨利酮能改善充血性心衰患者的运动能力,但心功能的提高及肺嵌压的下降可能不是其主要机制。
Tolerance exercise test in 20 patients with congestive heart failure(CHF) treated by digitalis was studied. Cardiac index (CI) and pulmonary arteriole wedge pressure (PAWP) were measured with invasive technique simultaneously. Then China-made amrinone(AMR)was administered for 15 d and the indices of all of them were repeated. The results showed that the exercise tolerance time in those patients was prolonged significantly but CI and PAWP were not correlated with the tolerance exercise time before and after AMR treatment. These findings suggest that AMR can improve the exercise capacity (EC) in patients with CHF but the increase in cardiac function and increase in PAWP probably are not the main cause of the improvement in EC.
出处
《第三军医大学学报》
CAS
CSCD
北大核心
1990年第4期288-29,共1页
Journal of Third Military Medical University
关键词
氨利酮
心力衰竭
运动试验
amrinone, China made
heart failure, congestive
exercise test
