摘要
目的:比较两种不同表面处理的种植体在植入早期表面沉积物的差异及其骨组织反应。方法:将表面经双重酸-双氧水-热处理和双重酸处理的种植体分别植入兔子胫骨内,然后,采用带能谱分析的扫描电镜观测2、4、8周带种植体的骨组织。结果:植入2周后在两组种植体表面均沉积富含钙磷层;4周时这层结构大部分消失,但双重酸-双氧水-热处理组可见较多的骨生成细胞附着在种植体表面并形成新骨。8周时两组种植体表面均附着一些新骨,但以双重酸-双氧水-热处理组相对较多。结论:两组种植体在植入早期表面均可形成富含钙磷层。
Objective： To compare the surface apposition and the bone response at early period of implantation in two differently treated implants. Methods ： The implants were subject to double acid-etched H2O2/HCl-heat treatment and double acid-etching treatment, and then randomly implanted into the tibia of rabbits. After 2,4,8 weeks of follow up,the bone specimens containing implants were prepared and examined by a field emission SEM and EDX. Results： A layer rich with calcium and phosphorus was clearly demonstrated on the implants surface of both groups after 2 weeks of implantation, but it was mostly disappeared after 4 weeks. There were large amount of osteoblasts cells on double acid-etched-H2O2/HCl heat treated implants surface indicating the initiation of osteogenesis. After 8 weeks of implantation some new bones were attached on the implants surface in both groups, more bones attached were showed on double acid-etched- H2O2/HCl-heat treated implants surface. Conclusion： A calcium and phosphorus-rich layer was formed on the implants surface of both groups at early period of implantation.
出处
《浙江大学学报（医学版）》
CAS
CSCD
2006年第5期472-478,共7页
Journal of Zhejiang University(Medical Sciences)
基金
浙江省医药卫生优秀青年科技人才专项科研基金(2004QN016)
浙江省科技计划重点资助项目(2005C23006)
