摘要
目的考察再造胶囊中黄芪甲苷的最佳提取工艺。方法通过正交实验,以干膏收率和黄芪甲苷总量为指标,考察加水量、煎煮时间、乙醇浓度等对提取效果的影响。结果再造胶囊中黄芪甲苷的最佳提取工艺为加水煎煮3次,第1次加10倍量水煎煮2h,第2次加8倍量水煎煮1h,第3次加6倍量水煎煮1h,药液合并,浓缩至相当于每1ml含1.5g生药,加乙醇至含醇量70%(v/v),静置过夜,取上清液滤过,滤液回收乙醇至尽。结论最佳提取工艺提取率高、简单、方便。
Objective： To optimize the preparation process of Astragaloside Ⅳ in Zaizao capsules. Methods： The optimum preparation process was investigated by L9 （3^4 ） orthogonal design as the astragaloside Ⅳ and total amount of dry ointment content index. The chief factors influencing the extraction efficiency were as follows： times of added water, the time of extraction et. Conclusion： Astragaloside Ⅳ＇s content is high. The method is reliable, accurate and easy to operate It is up to the mustard.
出处
《湖北中医学院学报》
2006年第3期27-28,共2页
Journal of Hubei College of Traditional Chinese Medicine
关键词
黄芪甲苷
薄层扫描法
提取工艺
正交设计
Astragaloside Ⅳ
TLC-scanning
Extraction process
Orthogonal design
