摘要
目的分析糖尿病合并类鼻疽伯克霍尔德菌败血症的临床特点,并探讨其诊疗策略和措施。方法回顾性分析21例糖尿病合并类鼻疽伯克霍尔德菌败血症的临床特点、诊疗经过和转归。结果类鼻疽伯克霍尔德菌败血症临床表现多样化,缺乏特异性,常表现为急性暴发性败血症和常伴组织器官脓肿形成及易诱发糖尿病酮症酸中毒(DKA),病情凶险,误诊率和死亡率高且可选用的有效抗生素较少,易复发,治疗周期长。结论早期诊断,尽早足量应用敏感抗生素,有脓肿者宜配合外科治疗,以及使用胰岛素积极控制好血糖和加强支持疗法是治疗成功的关键。
Objective To analyze the clinical characteristic of diabetes mellitus patients with Bburkholderia pseudomallei septicemia and the strategy of diagnosis and treatment. Methods The clinical characteristic, diagnosis, treatment and prognosis of 21 diabetes mellitus cases with Burkholderia pseudomallei septicemia were retrospectively analyzed. Results The clinical manifestations of the patients were diverse without special features, mainly with the manifestations of acute fulminant septicemia, diabetic ketoacidosis, abscesses in tissue or/and organs with high mortality and misdiagnosis rate as well as prone to relapse and a long duration of treatment as there were a few antibiotics effective for the disease. Conclusion Early diagnosis, a prolonged course of high - dose intravenous use of antibiotic, drainage of abscesses, insulin therapy and supportive therapy are the key measure for successful treatment of the patients.
出处
《中国热带医学》
CAS
2006年第10期1750-1752,共3页
China Tropical Medicine
关键词
糖尿病
类鼻疽伯克霍尔德菌
败血症
Diabetes meUitus
Burkholderia Pseudomallei
Septicemia
