摘要
报道１９８８年１月至１９９４年１２月所见１０６例扁桃体癌中有１５例淋巴上皮瘤样癌（ＬＥＬＣ），占１４％。对１５例ＬＥＬＣ作了免疫组化和组织病理学观察，采用原位杂交技术进行了ＥＢ病毒编码的小ＲＮＡ（ＥＢＥＲｓ）检测。结果表明：（１）癌细胞的形态与鼻咽非角化癌尤其是未分化癌类同，增殖活跃，有７例（４６％）ＬＥＬＣ的癌细胞呈Ｐ５３异常表达。（２）在癌细胞周围及癌巢间，有大量的淋巴类细胞浸润，巨噬细胞和树状突细胞丰富。（３）１０例（６７％）ＬＥＬＣ的癌细胞核内检测到ＥＢＥＲｓ。由于扁桃体ＬＥＬＣ具有一定的形态特征，与ＥＢ病毒感染相关，在临床病理诊断中宜将其作为扁桃体癌的一种特殊类型加以重视。
Measurements of fetal umbilical arterial blood flow velocity were made in late period in 312 pregnancies.29 pregnancies were found with intrauterine growth retardation.Significant increaces of S/D(the ratio of systolic flow velocity/diastolic flow velocity)、PI(pulsatility index)and RI(resistance index)were found in the patient with intrauterine growth retardation(IUGR)(S/D 3.58±1.16,PI 1.17±0.29,RI 0.73±0.18;in normal pregnancy S/D 2.68±0.76,PI 0.92±0.22,RI 0.60±0.09).The FBVR(Fast Blood Volume ratio)in IUGR(0.51±0.06)was decreased sigificantly ( P <0.0005) compared with that of normal pregnancy(0.57±0.05).This changes may be associated with the decrease of the blood volume pumped by the heart or the increase of the resistance in placenta.One patient with stillborn fetus was found a great increase in the ratio of S/D、PI、RI and decrease in FBVR. Absence of end diastolic velocity wave forms was found before the dead of the fetus in this patient.
出处
《中山医科大学学报》
CSCD
1996年第3期177-180,共4页
Academic Journal of Sun Yat-sen University of Medical Sciences
关键词
扁桃体肿瘤
病理学
鳞状细胞癌
EB病毒
fetal growth retardation
umbilical arteries
blood flow velocity
