摘要
采用反转录聚合酶链反应，从40例输血后丙型肝炎和30树非甲非乙非丙非丁非戊型肝炎（HNA－E）患者的血清中检测庚型肝炎病毒核酸（HGVRNA），阳性率分别为10．0％（4／40）和6．7％（2／30）。对6例庚型肝炎的临床和病理初步观察提示该病具有以下特点：（1）主要通过输血感染；（2）很少出现黄疸，ALT多在100U／L以下；（3）临床症状较轻，多系体检发现，（4）一般降酶护肝药很难奏效，病情容易反复；（5）慢性化发生率较高；（6）肝脏病理改变较轻，多属CPH。
In this article HGV RNA was detected by reverse transcription polymerase chain reaction (RT-PCR) in 40 cases of patients with post transfusional hepatitis C and 30 patients with non A to E. And it was foundthat the positive rate of HGV RNA was10. 0% (4/40) in post' transfusional hepatitis C and 6. 7% (2/30) in hepatitisnon A to E respectively. The clinical and pathological observations showed that these 6 patients with hepatitis Ghad following characteristics: (1) infection was chiefly transmitted from blood transfussion; (2)were slight clinicalsymptoms; (3) jaundice occured rarely;(4) general treatment was not satisfactory and the disease was liable to easily relapsed; (5)the disease mostly inclined to chronicity; (6)damage of liver tissue was slight, but like just aschronic persistance hepatitis.
出处
《江苏医药》
CAS
CSCD
1996年第12期818-820,共3页
Jiangsu Medical Journal
关键词
庚型肝炎
聚合酶链反应
临床
病理学
Hepatitis G
Polymerase chain reaction
Clinical features
Pathological change
