摘要
目的观察中粒细胞减少症(neutropenia)用粒细胞集落刺激因子(G-CSF)治疗后白细胞(WBC)变化情况。方法对本院2002～2004年血液肿瘤科WBC减少住院病人200例和门诊病人4例,均已进行G-CSF治疗作为治疗组,对照组50例。结果治疗组总有效率为92.6%,时间3～14d不等,WBC数量从(2.39±1.20)×109/L上升到(8.60±2.86)×109/L,中性粒细胞(ANC)数量从(1.10±0.80)×109/L上升到(3.60±1.16)×109/L;对照组上升率为58.0%。治疗组和对照组WBC和ANC变化比较差异有显著性,P<0.01。血红蛋白、血小板其数量无明显变化。结论用G-CSF治疗白细胞减少症WBC和ANC上升显著。
[Objective] To observe the blood routine change of the leucopenia cases after using Granulocyte Colonyte Stimulating Factor. [Methods] 254 cases from 2003 to 2004 suffering from leukopenia were chosen in our study. 204 cases of them （treating group） were given Granulocyte Colonyte Stimulating Factor for treating, the other 50 were for contrast. Their chang of blood routine were observed. [Results] The effective rate in the treating gaoup was 92.6%. The number of WBC raised from （2.39±1.2）×10^9/L to （8.60±2.86）×10^9/L, the number of ANC raised from （1.10±0.80）×10^9/L to （3.60±1.16）×10^9/L. While in the contrast group, the effective rate was 58.0%. There was statisaicaUy significant difference between the two groups （P 〈0.01）. [Conclusions] The number of WBC and ANC increase singnificantly after the traeting of granulocyte colonyte stimulating factor.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2006年第17期2660-2662,共3页
China Journal of Modern Medicine
关键词
粒细胞减少症
粒细胞集落刺激因子
血常规
neutropenia
granulocyte colonyte stimulating factor
, blood routine
