摘要
目的探讨葡萄糖酸钙、缩宫素、米索前列醇联合应用预防剖宫产产后出血的效果。方法选385例剖宫产者随机分三组：单药组120例(缩宫素组)；两联药组(缩宫素加米索前列醇组)130例；三联药组(葡萄糖酸钙加缩宫素加米索前列醇组)135例。结果测得术中出血及术毕阴道积血量：单药组(300±50．24)ml,两联药组(220±30．83)ml,三联药组(150±45．52)ml,各组出血量比较差异有统计学意义(P＜0．05)；术后2h累计出血：单药组(400±45．53)ml,两联药组(260±60．43)ml,三联药组(210±50．54)ml,各组出血量比较差异有统计学意义(P＜0．05)。结论三药联合应用能更好地预防剖宫产术中及术后出血,且用药方便、安全、经济。
Objective To discuss effect on prevention of postpartum hemorrhage of caesarean section by using calcium gluconate combined with oxytocin and misoprostol. Methods 385 cases of caesarean section were selected and randomized into O （Oxytocin） group and OM（ Oxytoein ＋ Misoprostol） group and COM（ Calcium glueonate ＋ Oxytocin ＋ Misoprostol） group. Results The mean operative blood loss in O group and OM group and COM group were （300 ±50.24） ml, （ 220±30.83） ml, （ 150 ± 45.52） ml. The amount of the mean operative blood loss of COM group was significantly lower than those of O group and OM group（P 〈 0.05）. The amount of bleeding of 2 hours after delivery in O group and OM group and COM group were （400±45.52）ml, （260 ±60.43）ml and （210 ± 50.54） ml. The amount of bleeding of COM group was significantly lower than those of O group and OM group（P 〈 0.05）. Conclusion The prevention by used calcium gluconate combined with oxytocin and misoprostol is efficient in reducing the amount of postpartum hemorrhage of caesarean section. The operation of medicine is easy and safe and economic.
出处
《中国基层医药》
CAS
2006年第8期1246-1247,共2页
Chinese Journal of Primary Medicine and Pharmacy
