摘要
准确评价终末期肝病患者的肝脏储备功能有利于临床医生为患者选择个体化的治疗方案,特别是近年来肝移植技术的发展迫切需要一个精确、简便和客观的标准。肝功能分级(Child-Turcotte-Pugh,CTP)分级用于临床已有40多年了,在判断终末期肝病的肝脏储备功能上越来越显示其局限性。终末期肝功病模型(Model for End-stage Liver Disease,MELD)是近年来创立的判断终末期肝病患者的肝脏储备功能的新方法,其在临床应用尤其在肝移植方面已显示出许多优越性。该文主要对CTP分级和MELD评分的产生、特点、临床应用及存在的问题作一综述。
To evaluate the liver store function of patients with liver disease in teminal stage is helpful for doctors to select individualized therapeutic regimen for the patients, especially in recent years, an precise, simple and objective criteria is needed urgently with the development of liver transplantation. Although the CTP has been used for more than 40 years, its limitation is becoming more and more obvious in liver store function judgement of liver disease in its teminal stage. The Model for End-stage Liver Disease（MELD）is a new method to evaluate the liver store function of the end-stage liver disease in recent years. It has showed much more advantages in clinical practice, especially in liver transplantation. This article reviews CTP and MELD about their designs, characters, clinical applications and existing problems respectively.
出处
《医学综述》
2006年第17期1075-1077,共3页
Medical Recapitulate
关键词
终末期肝病
CTP分级
MELD评分
The endstage liver disease
The classification of Child-Turcotte-Pugb
The grade of Model for End-stage Liver Disease
