摘要
Ezrin蛋白是细胞骨架与细胞膜之间的连接蛋白,参与了微绒毛的形成并与细胞形态的维持、运动、黏附及生存有关,对其结构和功能都有详细的研究。目前许多研究表明Ezrin蛋白与肿瘤的发生、转移和预后相关。对Ezrin蛋白在肿瘤中的全面研究,为肿瘤的诊断、治疗和预后评价提供新的思路和标准。
Ezrin protein function as molecular linker between the actin-cytoskeleton and the plasma membrane, which involves in the formation of microvilli and the maintenance of cello-morphology, movement, adhereance as well as survival, intimate studies of its structure and function have been done. At present many studies indicate that Ezrin involves in the tumor development and tumor metastasis, relate to prognosis. To study Ezrin protein in tumor will provide us other way and standard for diagnose and treatment of tumor and prognostic evaluation.
出处
《肿瘤研究与临床》
CAS
2006年第9期638-640,共3页
Cancer Research and Clinic
关键词
EZRIN蛋白
肿瘤
预后
Ezrin protein
Tumor development
Tumor metastasis
Prognosis
