摘要
目的:回顾研究结直肠癌单个转移淋巴结的分布情况,预测结直肠癌中前哨淋巴结(SLN)概念的适用性及分布情况,并为进一步结直肠癌SLN的前瞻性研究提供参考。方法:收集中山大学附属肿瘤医院腹科1998年1月～2003年9月根治术后常规病理检测只有一个淋巴结转移的125例结直肠癌患者有关资料。其中男67例(53.3%),女58例(46.5%);平均年龄55.8岁(25～82岁)。结果:125例患者共计淋巴结1065枚,平均每例患者8.52枚(1～32枚)。单个转移淋巴结分布情况结果显示肠旁组淋巴结转移81例(64.8%),中间组淋巴结转移40例(32.0%),中央组淋巴结转移4例(3.2%)。非肠旁组织转移的“跳跃”转移44例(35.2%)。结论:大部分结直肠癌SLN分布于肠旁,但相当部分可出现“跳跃”现象。必须进行深入的前瞻性研究,探索理想的结直肠癌SLN示踪方法,全面研究结直肠癌SLN的分布规律。
Objective： To investigate the solitary metastatic lymph node distribution and clinical significance in colorectal cancer and to provide novel methods for further prospective study. Methods：Between January 1998 and September 2003,125 consecutive patients undergoing resection for clinically localized CRC at the abdominal surgery department of Sun Yat-sen university cancer center were enrolled. These patients have the solitary lymph node metastasis. Results：The study group consisted of 69 men and 60 women whose average age was 55.8 years old （ range 25 to 82 years ）. A total of 1 065 nodes （ average 8.52 per patient ; range 1 to 32） were identified in this study group. The results revealed that the solitary metastatic nodes were found in the nearest pericolorectal nodal area in 64.8% of cases. Among 44 cases （ 35.2% ） of colorectal cancer with “skip” metastasis . Conclusion ： The loction of SNLs in colorectal cancer is random and multidirectional, and the rate of “skip”metastasis is much higher than expected. It is necessary to design a prospective study to evaluate the role of SLNs in colorectal cancer.
出处
《临床肿瘤学杂志》
CAS
2005年第4期379-381,共3页
Chinese Clinical Oncology
关键词
结直肠癌
前哨淋巴结
淋巴结
转移
Colorectal cancer
Sentinel lymph node
Lymph node
Metastasis
