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谷氨酰胺和甘氨酰-谷氨酰胺对断奶仔猪小肠黏膜的影响 被引量:22

Effects of Glutamine and Glycyl-Glutamine on Intestinal Mucous in Weaned Piglets
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摘要 选用21日龄断奶的杜大长仔猪108头,按试验要求分为3组,每组3个重复,每重复12头。分别饲喂含1%谷氨酰胺(G ln)和0.3%的甘氨酰-谷氨酰胺(G ly-G ln)的日粮,试验期14天,在断奶前、断奶后7天和14天分别屠宰取样。试验结果表明:(1)断奶后7天,日粮中添加G ln和G ly-G ln可显著提高小肠各段绒毛的高度,降低隐窝深度,断奶后14天添加G ly-G ln可显著提高十二指肠、回肠绒毛高度。(2)断奶后7天和14天,添加G ln和G ly-G ln均可显著提高空肠黏膜蔗糖酶和麦芽糖酶活性,对乳糖酶活性无显著影响。(3)断奶后7天,添加G ln和G ly-G ln可降低血浆二胺氧化酶(DAO)活性,提高空肠黏膜DAO活性,断奶后14天,添加G ly-G ln可显著提高空肠黏膜DAO活性。 One hundred and eight piglets weaned at 21d age were allocated to three treatments, each of which had 3 replicates, 12 piglets per replicate. The three treatments were fed basal diet (control group) , basal diet + 1% glutamine ,and basal diet +0.3% glycyl- glutamine respectively. The results show that: (1) Piglets fed glutamine or glycyl -glutamine have significantly higher intestinal villus height and lower crypt depth at 7d post weaning. Piglets fed glycyl - glutamine have significantly higher duodenum and ileum villus height at 14d post weaning. (2) Supplement with glutamine or glycyl - glutamine significantly increases the activities of sucrase and mahase in jejunum mucous at 7d and 14d post weaning, no significant difference for lactase activity. ( 3 ) Supplement with glutamine or glycyl - glutamine significantly decreases the activity of diamine oxidase (DAO) in blood and increases the activity of DAO in jejunum at 7d post weaning. Supplement with glycyl - glutamine significantly increases the activity of DAO in jejunum at 14d post weaning.
作者 杨彩梅
出处 《中国粮油学报》 EI CAS CSCD 北大核心 2006年第4期119-123,共5页 Journal of the Chinese Cereals and Oils Association
基金 浙江省教育厅资助项目(G2002097)
关键词 谷氨酰胺 甘氨酰-谷氨酰胺 小肠黏膜 断奶仔猪 glutamine, glycyl - glutamine, intestinal mucous, piglet
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