摘要
目的:了解住院高血压患者中睡眠呼吸障碍(sleepdisorderedbreathing,SDB)的患病情况及对肾功能的影响。方法:对107例高血压患者行随机的床旁EMBLETTA9导联睡眠HOLTER诊断,监测8h的睡眠,筛选出SDB患者,分组分析血肌酐、尿酸、电解质等指标。结果:81例合并SDB,患病率75·7%,其中男性患病率82·0%,女性患病率67·4%。合并SDB的高血压患者血尿酸水平明显增高,而血肌酐水平、肌酐清除率无明显差异。结论:高血压住院患者中SDB患病率明显高于一般人群;合并SDB的高血压患者血尿酸水平明显增高。
Objective： The prevalence of sleeping disordered breathing（SDB） in hospital adult patient with hypertension, and the influence of renal function were investigated. Method ： Sleeping Hoher was performed 8 hours in 107 patients with hypertension in hospital. Parameters of renal function （serum creatinine, creatinine clearance, serum uric acid） were compared with Independent-Samples T Test. Result： Prevalence of SDB, defined as an apneahypopnea index of ≥ 5 obstructive events per hour of sleep, was 75.7% in patients with hypertension in hospital, 82.0% in men and 67.4% in women. Serum uric acid in severe SDB patients was significantly higher than that in patients without SDB [ （430.17 ± 117.30） μmol/L vs （ 316.48 ± 108.99 ） μmol/L, P = 0.003 ]. Conclusion ： Our results suggest that a higher prevalence of SDB in patients with in hospital hypertension than people without hypertension. Serum uric acid is increased significantly in patients accompany SDB. Further prospective studies will have to be done to elucidate the pathophysiological mechanicsms.
出处
《心肺血管病杂志》
CAS
2006年第3期150-152,共3页
Journal of Cardiovascular and Pulmonary Diseases
关键词
睡眠呼吸障碍
高血压
血尿酸
Sleep disordered breathing
Hypertension
Serum uric acid
