摘要
目的:探讨黄芪注射液对鸡胚绒毛尿囊膜(chorioallantoicmembrane,CAM)血管生成的影响。方法:种蛋随机分为5组,孵育7d后,将高、中、低剂量黄芪注射液穴Astragalusmembranaceusinjec鄄tion,AMI雪及生理盐水(NS)、成纤维细胞生长因子(EGF)对照品分别加于CAM表面的载体上,作用后制备CAM标本,解剖显微镜下计数新生血管数目。结果:黄芪注射液具有明显的促进鸡胚绒毛尿囊膜血管生成的作用,与NS阴性对照组相比有显著性差异(P﹤0.05),但药效低于EGF阳性对照组(P﹤0.05)。结论:黄芪注射液可促进鸡胚绒毛尿囊膜血管生成。
Objective ：To explore the effect of angiogenesis of astragalus membranaceus injection （AMI） on the chick embryo chorioallantoie membrane（CAM）model. Methods：Fertilized eggs were incubated for 7 clays at 37.8 ℃, and randomly divided into 5 groups. Then treated with NS, different dose of AMI and EGF respectively. After incubated for another 3 days, counted the number of the first and second grade blood vessels. Results：In a test experience,the proliferation of capillaries in the therapy groups was obviously increased compared with NS group（P 〈 0.05）, but the effect was lower than EGF group （P 〈 0.05）Conclusion ： AMI can stimulate angioge nasis of chick embrgo CAM model .
出处
《中医儿科杂志》
2006年第3期12-15,共4页
Journal of Pediatrics of Traditional Chinese Medicine
关键词
血管生成
绒毛尿囊膜
黄芪注射液
Angiogenesis
chorioallantoie membrane
astragalus membranaceus injection
