摘要
目的探讨经皮球囊二尖瓣成形术(PBMV)治疗重度二尖瓣狭窄(MS)伴心房颤动(AF)近期的临床疗效。方法比较47例重度MS合并AF患者(AF组)和63例MS窦性心律患者(窦律组)PBMV手术的成功率,手术前后的临床疗效,血流动力学以及超声心动图指标的改变。结果两组手术成功率分别达到95.7%与96.4%,PBMV后两组临床症状均获明显改善,治疗前后NYHA心功能明显改善,房颤组心功能改善与窦律组相当。PBMV后血流动力学以及超声心动图指标如左心房压力、跨瓣压差、肺动脉压力、左心房内径及二尖瓣口面积明显增大明显下降(P均<0.001),但房颤组下降差值均较窦律组下降幅度小(P<0.05)。结论PBMV能使AF患者获得明显的临床和血液动力学改善,AF本身不影响PBMV成功率。
Objective To investigate the effectiveness of percutaneons balloon mitral valvuloplasty in patients with severity mitral stenosis and artrial fibrillation(AF). Methods The successful rates of PBMV, changes of hemodynamic and echocardiographic indices and complications after PBMV were observed in 47 patients with MS and AF and 53 patients with MS and sinus rhythmia. Results The success rates were 95.7 % and 96.4 % respectively in two groups. The clinical symptoms and the NYHA cardiac functions were improved after PBMV in both groups. The improvement of cardiac function in AF group was equal to sinus rhythmia group. The hemodynamic and echocrardiographic indices modified markedly in both groups just after PBMV, such as left atrial pressure, pulmonary pressure and left atrial diameter(P 〈 0.001 respectively ) especially in sinus rhythmia group ( P 〈 0.05). The mitral valve area were larger post-PABMV than before PBMV in two groups (P〈0. 01 respectively). Complications was 4.3% and 3.6% respectively in two groups. There was no difference between two groups. Concision PBMV is effective in improving clinical symptoms and hemodynamics in patients with MS and AF. AF itself doesn' t affect the success rate.
出处
《广西医学》
CAS
2006年第8期1159-1161,共3页
Guangxi Medical Journal
关键词
二尖辩狭窄
心房颤动
二尖辩球囊扩张成形术
Mitral stenosis
Atrial fibrillation
Percutaneous baUon mitral valvuloplasty