摘要
糖尿病肾病的主要临床表现是尿蛋白增加,作者通过观察89例非胰岛素依赖型糖尿病(NIDDM)患者24小时尿蛋白量及空腹血糖,病程、年龄、血压、红细胞聚集的改变,用电脑进行多因素逐步回归处理,分析探讨影响 NIDDM 患者尿蛋白的因素。结果表明,患者24小时尿蛋白含量与红细胞聚集、病程、空腹血糖成显著正相关,且它们对24小时尿蛋白含量的影响大小依次为红细胞聚集、病程、空腹血糖。
The development of diabetic nephropathy is associ- ated with microcirulation abnormalities.We studied the relationships between 24-hour urinary protein levels and age,duration of diabetes,blood pressure,fasting blood glucose,erythrocyte aggregation in 89 NIDDM pa- tients.Using step-wise logistic regression analysis,the posi- tive correlation was found between the 24-hour urinary pro- tein levels and erythrocyte aggregation (b=0.5138,P=0. 0215),duration of diabetes(b=0.1030,P=0.0013),fasting blood glucose(b=0.0494,P=0.046).The results suggested that erythrocyte aggregation changes is a significant risk fac- tor for progression of diabetic nephropathy
出处
《广东医学》
CAS
CSCD
1996年第10期654-656,共3页
Guangdong Medical Journal
