摘要
为探讨原发性食管单纯腺癌的临床生物学特征及根治性切除术后放疗对其预后的影响。对比分析２７例随机采用不同方式治疗者的临床资料及随访结果。术后组织学显示其残端受侵率为２６．０％，肿瘤外侵发生率为４０．７％，淋巴结转移率为５１．９％。术后５年生存率Ⅰ、Ⅱ期者４５．５％，Ⅲ、Ⅳ期６．７％；根治性切除术后加用放疗者４５．５％，未加用放疗者则为零，具有显著性差异。结论：本病的生物学特性与肺腺癌基本相似，其发生可能与Ｂａｒｒｅｔｔ食管无明显关系。影响本病预后的因素主要为临床分期、肿瘤外侵程度和有无淋巴结转移；根治性切除术后能否加用有效的放射治疗对其预后至关重要。
Aim:Thispapermainlydiscussestheclinicalbiocharacteristicofsimpleprimaryesophagealadenocarcinoma(SPEA)andtheeffectorradiotherapyonprognosisafterradicaloperation.Methods,Theclinicalmaterialsandfollow-upresultsof27casesofSPEAtreatedbydifferenttypesoftherapychosenatrandomweresubjectedtocontrastanalysis.Resulis,Thepostoperativehistologyshowedthattherespectiverateofstumpinfiltration,extraesophagealextension,lyrnphnodemetastaseswas26.0%,40.%and51.9%;thefiveyearsurvivalrateofpatientsinⅠ+Ⅱclinicalstageswas45.5%,linⅢ+Ⅳ6.7%,andthatofpatientswithpostoperativeradiotherapywas45.5%andwithoutradiotherapy0%.Conclusion:Thebiocharacteristicofthesimpleesophagealadenocarcinomaisbasicallysimilartothatofthelungadenocarcinoma.ltsdevelopmentisprobablynotrelatedtotheBarrett'sesophagus.Theclinicalstages,extraesophagealextensionandlymphnodemetastasesoftheprimarytu-morarethekeyprognosticfactors.Thetimelyandeffectivepostoperativeratliotherapyisofgreatim-portancetoprognosis.
出处
《中华胸心血管外科杂志》
CSCD
北大核心
1996年第5期293-295,共3页
Chinese Journal of Thoracic and Cardiovascular Surgery
关键词
食管肿瘤
腺癌
外科手术
EsophagealadenocarcinomaSurgicaltreatmentRadiotherapy
