摘要
原发性食管单纯腺癌较少见,1975~1994年我院共收治18例,均经手术病理证实,术后仅1例生存超过3年,预后较食管鳞癌差。食管腺癌的组织来源有四种:食管腺体、异位胃粘膜、食管粘膜上皮的基底细胞或Barrett食管,其中以来自Barrett食管恶变者占大多数。其病理组织学可分为单纯腺癌、腺鳞癌、腺棘癌、腺样囊性癌和粘液表皮样癌。最终诊断须靠病理组织学检查,采用以手术为主的综合治疗可望提高生存率。
Primary esophageal adnocarcinoma simplex is rare. Eighteen cases were treated in our hospital during the period from l975 ̄1994. All patients were treated by surgery and confirmed by pathology. Only one of them survived more than 3 years.The prognosis was worse than that of the squamous cell carcinoma of the esophagus.Esophageal adnocarcinoma is of four origins:esophageal intrinsic gland, ectopic gastric mucosa, basal cell of the esophageal epithelium mucosae, and Barrett's esophanus. Most of them originate from malignization of Barrett's esophagus.Histopathological classification:adnocarcino ma simplex, adenosquamous cell carcinoma, adenoacanthoma, adenoid cystadenocarcinoma and mucinous epidermoidoma.Confirmed diagnosis of the disease depends on pathological examination. cOmbination therapy composed mainly of operation possibly enhance the survival rate of patients.
出处
《实用癌症杂志》
1996年第3期185-186,共2页
The Practical Journal of Cancer
关键词
单纯腺癌
食管肿瘤
外科手术
Esophagus Adnocarcinoma simplex Surgical treatment