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AgNOR定量研究在甲状腺结节良恶性鉴别及预后判定中的意义

SIGNIFICANCE OF AGNOR MORPHOMETRIC ANALYSIS IN DIFFERENlIATION AND PROGNOSIS BETWEEN BENIGN AND MALIGNANT THYROID NODES
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摘要 用AgNOR胶银染色技术检测了59例甲状腺良恶性结节(恶性33例、良性26例),正常对照5例,对细胞柱内AgNOR作了定量研究。发现良恶性结节间有转移的癌和未转移癌,良性结节和正常甲状腺之间AgNOR计数均有统计学意义。认为AgNOR定量研究对于良恶性结节、良性结节恶性变的监测及预后的判定均有意义。 In this study,the authors tested 59 benign and malignant thyroid nodes(26bcnign and 33 malignant nodes)and 5 normal nodes as controls by means of the argyrophilictochniquc of nuclcolus organizer regions(AgNORs ).AgNORs morphometric analysis of their nucleus was carried out.The result showed that the counting of AgNORs has statistical valucbetwcen benign and malignant nodcs,metastatic and nonmetastatic carcinoma,benign nodes andnormal thyroid The authors considered that AgNORs morphometric analysis is useful fordistinguishing benign and malignant nodes.supervising thc(tested) undorgoing of the malignantchange of bcnign nodes and judging prognosis.
机构地区 内蒙古医学院
出处 《肿瘤研究与临床》 CAS 1996年第3期154-155,共2页 Cancer Research and Clinic
关键词 甲状腺肿瘤 AGNOR 甲状腺病变 恶变 预后 Diseascs of thyroid Mctastasis Prognosis AgNOR
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