摘要
ＡｇＮＯＲ法检查恶性胸腹水６０例，良性胸腹水７０例，共１３０例。两组每核ＡｇＮＯＲ颗粒均值分别为４．３５±２．１８和１．８０±０．７９，有极显著差异（Ｐ＜０．０１）。表明该法对良恶性胸腹水有鉴别诊断价值。作者用ＡｇＮＯＲ法诊断恶性胸腹水的敏感性为７５．００％，特异性为８６．５４％，其敏感性明显高于细胞学检查敏感性３６．６７％（Ｐ＜０．０１）。另外，良性组中，４０例渗出液和２０例漏出液的ＡｇＮＯＲ颗粒均值分别为１．９３±０．９０及１．５３±０．４８，有显著差异（Ｐ＜０．０５）。提示该法可能有渗、漏出液鉴别价值。
Ascites and hydrothorax from 130 patients with different diseases were examined by the AgNOR technique. The mean number of AgNOR granules per nucleus in 60 malignant ascites and hydrothorax were 4.35±2.18 and 1.80 ±0.79, respectively. The AgNORs of the former were significant higher than those of the latter (P<0.01), which suggested that this technique was useful in differential diagnosis between benign and malignant ascites and hydrothorax. Further study has shown the positive rate of AgNOR to bemuch higher (75.00%) than that through pathological examination (36.67%) (P<0.01).In addition,40 cases of exudative effusions and 20 of transudative effusions in the benign group were observed to have the mean valuesof 1.93±0.90 and 1.53 ±0.48 respectively, which indicates that this technique could also be useful in identifying exudative and transudative effusions.
关键词
核仁组成区
胶银染色
胸水
诊断
胸部肿瘤
Nucleolus organizer region
AgNOR stain
Hydrothorax/Pathol
Ascites/pathol
Carcinoma/diag
Lung Neoplasms/diag
Pleural neoplasms/diag
