摘要
[目的]对复方尿素霜中尿素、维生素A的含量进行测定。[方法]运用紫外分光光度法。[结果]尿素的测定波长为428nm，在20—180μg／mL浓度范围内与吸收度呈良好的线性关系，平均回收率为99．73％，含量为（10．05±0．22）％；维生素A的测定波长为328nm，在4—20u／mL浓度范围内与吸收度呈良好的线性关系。平均回收率为99．41％，含量为（2．03±0．06）％，二者无相互干扰。对自制的3个批号的尿素霜中的尿素、维生素A的含量分别测定，符合外用制荆的含量要求。
[ Objective] This paper describes the determination of the contents of urea and VitA contained in the conpound urea cream with ultraviolet （UV） spectrometry. [ Results] The determined wavelength of urea is 428 nm and the concentration range of 20 - 180 μg/mL of urea possesses the good linear relationship with the absorbance. The average recovery of urea is 99.73% and the content of it is （10.05 ± 0.22）%. The VitA determination wavelength is 328 nm. VitA possesses the good linear relationship with the absorbance when within the range of 4 - 20 u/mL. The average recovery of VitA is 99.41% and the content o f it is （2.03 ± 0.06）%. There is no any interference between the two determinations described above. [Conclusion] The contents of there batch of self- made compound creams are determined which are in accordance with the requirement of the exterior preparation.
出处
《大连医科大学学报》
CAS
2006年第4期333-335,共3页
Journal of Dalian Medical University
