摘要
目的探讨肾移植术后血肌酐升高患者使用他克莫司(FK506)和雷帕霉素(RPM)的有效性。方法49例肾移植受者血肌酐升高至310～650μmol/L采用FK506、RPM、泼尼松三联用药。结果治疗8周后24例肾功能恢复正常,17例血肌酐明显下降,8例无效。结论FK506和RPM用于肾移植术后血肌酐升高早期患者是有效的。
[ Objective ] To study the efficacy of FKS06 and RPM to the patient following renal transplantation with increasing serum creatinine. [Method] 49 renal transplantation recipients with increasing serum creatinine between 310 to 650 μmol/L adopted triple immunosuppression therapy with FK506. RPM and Pred. [Result] After 8 weeks therapy, the renal function of 24 cases normalized, the serum creatinine of 17 cases descented obviously, 8 cases was ineffective. [Conclusion] FK506 and RPM have therapeautic effects on increasing serum creatinine following renal transplantation
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2006年第15期2348-2349,2352,共3页
China Journal of Modern Medicine
关键词
他克莫司
雷帕霉素
肾移植
治疗结果
tacrolimus
rapamycin
renal transplantation
therapeautic efficacy
