摘要
腺苷是包括中枢神经系统（ＣＮＳ）细胞外液在内的体液的正常组成成分，其正常水平为０．０３～０．３μｍｏｌ／Ｌ。ＡＴＰ合成与分解失衡的条件下明显升高，如缺血时可升高１０００倍之多。腺苷通过腺苷受体（ａｄｅｎｏｄｉｎｅｒｅｃｅｐｔｏｒ，ＡＲ）对ＣＮＳ具有多方面的生理与病理作用，被认为是ＣＮＳ的抑制性神经调质，具有神经保护作用。
Adenosine is one of the normal elements in they fluid including extracellular fluid within the CNS.Its normol level is 0. 03～0. 3μmol/L. When ATP's metabolism loses balance,for example, during ischemia, the level of adenosine increases dramatically,may reach as much as 1000 times of the normal. Adenosine plays many physiological and pathological roles in CNS via its receptors. It is recognized as an inhibitory neuromodulator playing a neuroprotective role in CNS.
出处
《生理科学进展》
CAS
CSCD
北大核心
1996年第4期313-318,共6页
Progress in Physiological Sciences
关键词
腺甙
腺甙受体
神经递质
Adenosine
Adenosine receptors
Neuromodulator
Neuroprotection
