摘要
目的探讨术中射频治疗在剖胸探查晚期非小细胞肺癌治疗中的作用和意义。方法2002年1月至2004年12月23例剖胸探查无法手术切除的晚期非小细胞肺癌患者行术中射频治疗为治疗组(n=23,A组),同期无法手术切除的晚期非小细胞肺癌30例给予化疗为对照组(n=30,B组),观察术后疗效、疼痛缓解程度、ECOG评分、术后生活质量。结果A组的治疗、疼痛缓解程度、ECOG评分及治疗后生活质量的好转率分别为65.22%、65.22%、60.86%、65.21%;B组为36.67%,33.33%,33.33%,30.00%。射频治疗组优于化疗组。(P<0.05)结论术中射频治疗可有效地提高不可切除的晚期非小细胞肺癌的术后疗效和生存质量,对于晚期非小细胞肺癌提供了新的治疗途径。
Objective To explore the significance and clinical effect on adiofrequency ablation for treating advanced non-small cell lung cancer. Methods intraoperafive From January 2002 to December 2004,53 cases with unresectable advanced non-small cell lung cancer were divided into two groups.Among them,23 cases received intraoperative radio-frequency ablation were as therapeutic group （Group A）and other 30 cases received chemotherapy were as control group（Group B）.The curative effectk,painful remission rate,ECOG score and quality of life were observed and compared.Results The efficacy rate of treatment result,pain remission, ECOG score ,and the life of quality in group A were 65.22%,65.22%,60.86%,60.86%, vs 36.67%, 33.33%, 33.33%,30.00% in group B respectively.The eflqcacy rate in group A higher than that in group B. （P〈0.05）. Conclusion Intraoperative radio-frequency oblation can improve postoperative curative effect and quality of life for unresectable advanced non-small cell lung cancer and it would provide a new therapeutic approach.
出处
《岭南现代临床外科》
2006年第4期281-283,共3页
Lingnan Modern Clinics in Surgery
关键词
晚期非小细胞肺癌
射频消融
术中
Advanced non-small cell lung cancer
Radiofrequency ablation
Intraoperation
