摘要
目的了解粤东地区妇女生殖道人乳头瘤病毒(HPV)感染率及型别分布情况。方法采用基因芯片技术对569例粤东地区妇女生殖道分泌物或脱落细胞进行18种高危型HPV和5种低危型HPV检测。结果569例患者中HPV感染275例,占48.3%。单一感染183例,占32.2%;双重感染67例,占11.8%;三重以上感染25例,占4.4%。275例阳性标本主要为高危型HPV16、18型,低危型HPV6、11型。结论粤东地区妇女生殖道病变患者HPV感染率较高,且以高危型HPV16感染率最高,因此,建立建全粤东地区妇女HPV监测体系,及早发现高危人群,最大限度地降低子宫颈癌对妇女生命和健康的威胁度。
Objective To understand human papilloma virus（HPV） infection situation of women in the east area of Guangdong. Methods HPV of 569 women in the east area of Guangdong were examined by gene chip technique. Results Of 569 cases investigated, 275 cases were HPV positive（48.3%）, 183 cases were single HPV type infection and 67 cases were double HPV types infection and 25 cases were multiple HPV types infection respectively. In 275 HPV positivecases, there were 147 cases of HPV-16, 31 cases of HPV-18, 83 cases of HPV-11 and 96 cases of HPV-6 respectively. Conclusions In the east area of Guangclong, HPV infection situation of women was severe, it should be very important to control HPV infection and treat cervical erosion effectively. The gene chip technique is a sensitive and specific method for examining HPV.
出处
《江西医学检验》
2006年第4期303-305,共3页
Jiangxi Journal of Medical Laboratory Sciences
基金
广东汕头市科学技术局重点科技项目2005-19
关键词
基因芯片
人乳头瘤病毒
生殖道病变
Gene chip technique
Human papilloma virus
Genital canal lesion
