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簇状钙化在钼靶X线诊断乳腺癌中的临床意义 被引量:15

The Clinical Significance of Clustered Calcifications in the Diagnosis of Breast Cancer by Mammography
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摘要 目的:探讨乳腺钼靶X线片中簇状钙化的影像特征,评估簇状钙化对早期乳腺癌诊断的临床意义。方法:对我院经手术和病理证实为乳腺良、恶性肿瘤,钼靶X线片发现以簇状钙化为主要征象的97例乳腺病例,就其钙化密度、数量、大小、形态及与肿块的关系分析乳腺癌钼靶X线片内簇状钙化的特征。结果:①97例乳腺分型显示,Ⅲ型索带导管型和Ⅳ中间混合型占86.6%,且乳腺癌居多。②乳腺癌94例,其中非浸润性有导管内癌和小叶原位癌共39例,占41.5%;浸润性有浸润性导管癌、浸润性小叶癌、硬癌、单纯癌、粘液癌和髓样癌共55例,占58.5%。乳腺良性病变3例,其中2例乳头状瘤病合并中度导管上皮不典型增生,1例乳腺纤维囊性增生症。③94例乳腺癌所见簇状钙化的形态特征主要呈杆状、细砂状、针尖状和混合钙化,钙化数目>20枚/cm2;在合并肿块的77例中肿块内外均有簇状钙化灶的34例,无合并肿块20例,占20.4%.结论:成簇钙化是1种中性分布形态,良、恶性均可,根据乳腺钼靶X线片内的钙化特征可作为临床评价其良、恶性的较可靠依据。成簇微小钙化在临床诊断乳腺癌方面具有重要意义。 Objective: To explore sign of clustered calcification found by mammography and evaluate its clinical values in the diagnosis of early breast cancer. Methods: To analyze the density, number, size, morphology and to compare with breast masses of the clustered calcification from 97cases breast with benign and malignant. All cases were confirmed by operation and pathology. Results: (1)Among 97 patients, the breast type of Ⅲ (cords -duct type) and Ⅳ (inter mixed type) were 86. 6%, the breast cancer is mostly; (2)In 94 cases breast cancer, 39 cases (41. 5% ) with noninvasive carcinoma, there are intraductal carcinoma and lobular carcinoma in situ ; 55 cases (58. 5% ) with invasive carcinoma, there are invasive ductal carcinoma, invasive lobular carcinoma, scirrhous carcinoma, carcinoma simplex, mucinous carcinoma and medullary carcinoma. In 3 cases benign papillomatosis, 2 cases with mezzo atypical intraductal epithelial cell hyperplasia intraductal , 1 cases carcinoma, invasive lobular carcinoma, scirrhoma carcinoma, carcinoma simplex, mucinous carcinoma, medullary carcinoma. In 3 cases benign papillomatosis, 2 cases with mezzo atypical intraductal epithelial cell hyperplasia intraductal , 1 cases cystic hyperplasia; (3)In 94 cases breast cancer, clustered rod - shaped, minute or sand - shaped and multiform calcified foci were the main kinds , the calcify number 〉 20 grains/ cm^2. In 77 cases of benign and malignant breast tumors, there are 20 (20. 4% ) singles mass, calcifications in mass appeared in 34 (79. 6% ) cases. Conclusion: The modality of calcifications was seen both in malignant and benign breast tumors. Their features of calcification are very valuable in the diagnosis of breast tumors, specifically of breast cancer in early stage.
出处 《中国妇幼保健》 CAS 北大核心 2006年第15期2155-2157,共3页 Maternal and Child Health Care of China
基金 厦门市科技基金资助项目(编号:3202Z20044003)
关键词 簇状钙化 乳腺肿瘤 钼靶摄像 Clustered Calcifications Breast tumors Mammography
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