摘要
目的：探讨用新生儿足跟全血血片TSH筛查新生儿先天性甲状腺功能减低症（CH）的切值和监测人群碘营养状况的可能性。方法：用TRFIA法筛查新生儿72h足跟全血血片TSH。结果：正常新生儿TSH频数呈正偏态分布，TSH〉5mU／L比率2．17％，99％分位数为6．89μU／ml，筛查确诊17例CH，其中5例（29．4％）TSH筛查时呈现低值9．11～18．0μU／ml。结论：本地区筛查CH切值以8μU／ml为宜，TRFIA筛查新生儿TSH〉5mU／L比例〈3％可作为人群碘营养状况正常的标志。
Objective ： To study the applicability of the CH cut - off by neonatal screening and of the monitoring of peopleg normal nutritional condition （TSH 〉 5mu/L percentage 〈 3% ） . Methods： Screen the TSH of full heel blood of neonate of 72h＇s old by TRFIA method. Results： the TSH frequency of normal neonate shows positively skew distribution （TSH 〉 5mu/L percentage 2. 17% , 99% quartile： 6.89 μU/ml） . 5 samples among 17 samples （29.4%） diagnosed to be CH by screening shows low level 9. 11 - 18.0 μU/ml when being screened. Conclusion： It＇s appropriate to set the CH cut -off of local area at 8 μU/ml TSH 〉 5 mu/L and percentage 〈 3% by TRFIA neonatal screening method can be regarded as people＇s normal iodic nutritional level.
出处
《中国妇幼保健》
CAS
北大核心
2006年第15期2099-2100,共2页
Maternal and Child Health Care of China
