摘要
目的：探讨外科医生乙型肝炎病毒（HBV）职业感染的监控方法。方法：在确定手术中HBV传染性和感染阈值的基础上，探讨外科医生HBV职业感染的监控方法。结果：HBV经单层手套感染的阈值为105ID／ml；经双层手套感染的阈值为106ID／ml；HBsAg阳性，HBeAg阳性和HBeAg阴性患者的传染性分别是0～109，102～109和0～106ID／ml；分别有19．2％，83．9％和3．2％患者的传染性超过单层手套的感染阈值，为手术中的传染源；86．7％的传染源分布在HBeAg阳性患者中，最大传染性为104ID／ml。80.8％的HBeAg阳性传染源的传染性超过双层手套的感染阈值．最大传染性为103 ID／ml。结论：在外科医生普遍进行HBV特异性免疫预防的基础上．以HBeAg取代HBsAg作为手术中HBV传染源监控指标是可行的。
OBJECTIVE：To evaluate supervising and controlling measures of surgeon who is infected by HBV during surgical operation were evaluated. Methods： On the basis of that HBV infectivity and infective threshold value were determined during surgical operation, supervising and oontrolling measures of surgeon who was infected by HBV during surgical operation were evaluated.Results： HBV infective threshold value of single layer gloves was 105 ID/ml, and that of double layer gloves was 106 ID/ ml. The infectivity of HBsAg positive, HBeAg positive and HBeAg negative patients was 0- 109, 102- 109 and 0 - 106 ID/ml, respectively. The rates of patients whose infectivity exceeded HBV infective threshold value of single layer gloves were 19.2%, 83.9 %, and 3.2 %, respectively. They were the HBV infective source in surgical operation. 86.7 % infective source were patients of HBeAg positive. The maximum infectivity of then, was 104ID/ml. Infectivity of 80.8% of HB3eAg positive infective source exceeded HBV infective threshold value of double layer gloves, with maximum infectivity was 103 ID/ml.Conclusions： On the basis of that susceptible surgeons are inoculated against HBV, it is feasible that HBeAg replaces HBsAg to be .served as a supervising and controlling index of HBV spread during operation.
出处
《现代预防医学》
CAS
北大核心
2006年第8期1478-1480,共3页
Modern Preventive Medicine
