摘要
结合内镜检查,从粘液池抽取清晨、空腹胃液,以其pH、游离酸、蛋白酶、粘液、胆汁酸及 DNA 值绘制直方图,对比三种慢性胃炎及正常组的图型特征,并用微机进行多元直线回归分析。结果显示正常组的胃液谱图为 pH居游离酸柱之半,游离酸、蛋白酶与粘液柱基本相平,胆汁酸和DNA甚低,约居粘液柱之1/4及1/5。三个胃炎组的胆汁酸、DNA柱均高于正常,游离酸则随着病理的进展而渐次降低,蛋白酶与粘液柱均以萎缩性胃炎组最低,浅表与浅表、萎缩性胃炎组虽均显著低于正常,但在二种胃炎组之间未见明显差异。相关分析表明:游离酸、蛋白酶及粘液分泌存在着显著的相随性,慢性胃炎时的粘膜分泌功能受损和组织损伤与胃内胆汁酸含量升高密切有关。
Gastric juice was collected from mucus pool through endoscopy.Thevalue of pH,free acid,pepsin,mucin,bile acid and DNA was measuredand drawed a straight squre diagram.The later one used as a gastricjuice manual,and would be compared in three kinds of chronic gastritisand normal control.The value of 6 indices of every case in wholegroup were analyzed the multiple linear regression with personalcomputer.It was demonstrated that the height of pH column was nearlythe half one of free acid,but the columns of free acid,pepsin andmucin were at same level,otherwise the high of bile acid and DNAcolumn both was so low,nearly the (1/4)-(1/5) height of mucin column inthe normal gastric juice manual.The columns of bile acid and DNAwere more higher than the normal control in all of the gastritisgroups,meanwhile,the column of free acid reduced gradually accordingthe pathologic process proceeding.The pepsin and mucin columns werelowest in atrophic gastritis,althrough they were also more lower thanmormal in superficial and superficial-atrophic gastritis,but there wasno significant difference between these two groups.The correctiveanalysis suggested that there was a significant following relationshipbetween the secretion of free acid,pepsin and mucin.It also suggestedthat the disorder of gastric mucosal secretory and injure of tissue would be closed related with the bile acid content in gastric juice.
关键词
胃病
胃液分析
胃液成分谱图
chronic gastritis
gastric juice analysis
gastric juice contents manual
multiple linear regression analysis of gastic juice contents
