摘要
结合内镜检查,从粘液池抽取清晨空腹胃液进行 pH、游离酸、蛋白酶、粘液、胆汁酸及 DNA 的同步测定,运用微机处理数据。结果证示:pH值以十二指肠消化性溃疡组最低;胃癌组最高;浅表、浅表萎缩及萎缩性胃炎依次递升,后者稍低于胃癌组;胆汁返流组居第三位。游离酸含量的分布情况与 pH 恰好对应相反。蛋白酶含量的分布情况与游离酸相仿,但在浅表性胃炎组即有明显的减少。所有胃病组的粘液含量均明显低于正常,而以胆汁返流组最低,其次是胃癌,萎缩性胃炎组的粘液含量与胃溃疡组相似。胃液胆汁酸以胆汁返流组最高,其次为胃癌,三种胃炎与二种溃疡病组间未见明显差异,但均显著高于正常。DNA 含量以胃癌组最突出,其次是胆汁返流组,其余情况与胆汁酸的分布特点相同。上述研究为临床进行胃功能检查及鉴别诊断提供了有价值的资料。
Gastric juice was collected from mucus pool through endoscopy,thevalue of pH,free acid,pepsin,mucin,bile acid and DNA wasmeasured simultaneously,and the data were aualyzed with personalcomputer.It was demonstrated that the value of pH was lowest inpeptic duodenal ulcer group and hightest in the group of gastric cancer,and raised gradually in superficial,superficial-atrophic and atrophicgastritis.The value of later one was only slightly lower than gastriccancer group,and bile regurgitation group was the third one.Thedistributive pattern of free acid content just as an oppositive manualof pH.The distributive pattern of pepsin content was similar to free acid,but it became reduced seriously at superficial gastritis group.The content of mucin was less significantly than normal in all gastricdiseases group,while the least one was bile regurgitation group,thenext one was gastric cancer group.The mucin content of atrophicgastritis was as same as in peptic gastric ulcer.The content of bileacid in gastric juice was hightest in bile regurgitation group,the nextone was gastric cancer group,but there was no significant differencebetween three kinds of gastritis and two kinds of peptic ulcer group;otherwise all of them were significantly higher than normal group.TheDNA content was conspicuously high in gastric cancer group and thenext one was bile regurgitation group,the others were similar to thedistributive pattern of bile acid.The study mentioned above wouldprovide some valuable materials for the gastric function measurememtand differential diagnosis in clinical proceduce.
关键词
胃病
胃液分析
多指标分析
chronic gastritis
gastric cancer
peptic ulcer
gastric juice analysis
