摘要
目的评价盐酸加替沙星片剂治疗呼吸系统或泌尿系感染的疗效与安全性。方法将呼吸系统及泌尿系统感染患者225例随机分为治疗组114例和对照组111例，治疗组给予盐酸加替沙星片口服，每次0．4g，qd；对照组给予左氧氟沙星片口服，每次0．2g，bid。两组疗程均为7-14d，观察疗效与不良反应。结果治疗组与对照组的临床有效率分别为88．60％和92．79％，细菌清除率分别为94．32％和96．63％，不良反应发生率分别为9．32％和11．97％；两组以上各指标比较均差异无显著性（均P〉0．05）。结论盐酸加替沙星片治疗呼吸道与泌尿系感染疗效确切，安全性好。
Objective To assess the therapeutic effectiveness and safety rate of gatitifloxacin hydrochloride in the treatment of infections of the respiratory or urinary system. Methods 225 patients with infections of the respiratory or urinary system were randomly divided into 2 groups ： the trial group （ n = 114） and control group （ n = 111 ）. Patients of the trial group were given each 0.4 g of gatitloxacin hydrochloride tablets PO, q. d. while those of the control group were given each 0.2 g of hvoiloxacin, PO, b. i. d.. The course of treatment in both groups lasted 7 - 14 days. The therapeutic effectiveness and adverse reactions of the drugs were kept under observation. Results In patients of the trial group and control group, the clinical effective rates were 88.60% and 92.79%, the bacteria elimination rates were 94.32% and 96.63% and the incidences of adverse reactions were 9.32% and 11.97%, respectivdy. Differences between the 2 groups with respect to the above mentioned data were insignificant （P〉0.05 ）. Conclusion Gatifloxcin hydrochloride was shown to be effective and safe in the treatment of infections of the respiratory or urinary system. KEY WORDS Gatifloxacin, hydrochloride; Levofloxacin; Bacterial infection
出处
《医药导报》
CAS
2006年第8期773-775,共3页
Herald of Medicine
