摘要
目的评价更昔洛韦治疗尖锐湿疣的疗效。方法61例尖锐湿疣患者随机分为两组。治疗组30例采用激光祛除疣体后静脉滴注更昔洛韦注射液,0.25 g.d-1,qd;对照组30例采用激光祛除疣体后静脉滴注阿昔洛韦注射液,每次0.25 g,tid。均连续治疗5 d。比较两组实验室检查结果、临床复发率和药物不良反应。结果对照组3个月内复发率为53.33%,治疗组为25.81%,治疗组复发率明显低于对照组(P<0.05)。两组药物不良反应发生率均较低。结论更昔洛韦治疗尖锐湿疣安全有效,不良反应少。
Objective To assess the therapeutic effectiveness of ganciclovir in the treatment of condyloma accuminatum （CA）. Methods Sixty-one patients with CA were randomly divided into 2 groups： the trial group and the control group.Patients of the trial group （ n = 31, 1 case excluded from the group later during the treatment course） and control group （ n = 30） were given each O. 25 g of ganciclovir and 0.25 g of aciclovir administered by intravenous instillation q.d. for 5 consecutive days, respectively, after the bodies of the warts in all of the patients had been extirpated with laser. The clinical recurrence rates and adverse reactions of the drugs in patients of the 2 groups were compared. Results The recurrence rate of CA within 3 months in patients of the trial group（25.81% ） was significantly lower than that in patients of the control group（53.33% ） （P〈0.05）. The incidences of adverse reactions of the drugs in patients of both groups were low. Condusion Ganciclovir was shown to be safe and effective in the treatment of CA.
出处
《医药导报》
CAS
2006年第8期771-772,共2页
Herald of Medicine
关键词
更昔洛韦
阿昔洛韦
尖锐湿疣
Ganciclovir
Aciclovir
Condyloma accuminatum
