摘要
对参与肉鸡胫骨软骨发育不良的酶、生长因子、维生素D及其受体,基因表达水平进行了综述,它们形成一个复杂的网络调控系统。阐述了它们在肉鸡胫骨软骨发育不良中所起的作用和变化。认为对参与干扰软骨细胞分化的各种基因的深入研究将为基因选择、消除机能紊乱、防治胫骨软骨发育不良的发生开辟新的途径。
Research advances in molecular mechanisms of tibial dyschondroplasia（TD） in broiler chickens were reviewed from the perspectives of enzymes, growth factors, vitamin D and its receptor, gene expression. These factors formed a complicated and integrated network. Functions of these factors and their changes in tibial dyschondroplasia were summarised. It was considered that identification of genes involved in the perturbation of chondrocyte differentiation in TD may provide new solutions to eliminate the disorder by genetic selection.
出处
《中国兽医科学》
CAS
CSCD
北大核心
2006年第7期587-591,共5页
Chinese Veterinary Science
基金
国家自然科学基金项目(30571370)中国博士后科学基金项目(2005037201)
