摘要
目的总结射频消融(RFA)治疗肿瘤直径≤5 cm小肝癌的疗效和经验。方法从1 9 9 9年9月-2 0 0 5年5月期间,采用RFA治疗肿瘤直径≤5 cm的原发性或转移性肝癌共1 3 0例,其中原发性肝癌8 6例,转移性肝癌4 4例。1 8例结合肝动脉栓塞化疗,2 0例同时行RFA联合瘤内无水酒精注射术。结果1,3年总累积存活率分别为9 1.3%,7 7.7%。治疗中7例发生并发症,分别为少量胆瘘、肠瘘、轻度皮肤灼伤,未发现与治疗相关的死亡。结论RFA对肿瘤直径≤5 cm的小肝癌是一种相对安全、有效的治疗方法,并有可能达到与手术切除相似的效果。
Objective To investigate the effect of radiofrequency ablation （ RFA ） in the treatment of small liver cancer. Methods In recent 6 years, 130 patients with primary or secondary liver cancer （ ≤ 5 cm in diameter） were treated by RFA, among which 86 cases were primary, and 44 cases were secondary liver cancer. Among the 130 cases, l 8 received RFA plus TAEC, and 20 had RFA combined with PEI. Results Overall 1- and 3-year survival rate was 91. 3 % and 77. 7 % respectively. Complications occurred in 7 cases, including biliary fistula, intestinal fistula, and slight burn of skin. There was no death in this series. Conclusions RFA is an effective and safe therapeutic approach for small liver cancer ≤5 cm in diameter. Its effect may be similar to that of surgical resection.
出处
《中国普通外科杂志》
CAS
CSCD
2006年第6期449-451,共3页
China Journal of General Surgery
基金
广东省科技厅科研基金项目
粤科计字(2001)281号
关键词
肝肿瘤/治疗
射频热毁损
栓塞
治疗性
注射
病灶内
Liver Neoplasms/ther
Radio Frequency Ablation
Embolization, Therapeutic
Injections, Intralesional
