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腹腔镜脑室肝膈间隙分流术腹腔端引流管固定方法的临床研究 被引量:19

CULTURE IN VITRO OF T CELL SUBGROUPS IN AXILLARY DRAINING LYMPHONODES OF PATIENTS WITH BREAST CANCER
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摘要 结合脑积水4例的腹腔镜脑室肝膈间隙分流术,就在腹腔镜下怎样放置固定脑室腹腔引流管进行了临床研究。在腹腔镜缝合打结法、腹腔镜钛夹固定法、腹腔镜穿刺皮下固定法3种方法中,穿刺皮下固定法具有创伤小,操作简单,手术时间短等优点,是理想的手术方法。 in order to find more effect cells of tumor infiltrating lymohocytes(TIL) as a source of primary lymphocytes acting in the adoptive immunotherapy to neoplasm, the authors studied 17 patients with breast cancer, culture in vitro of TIL and T lymphocytes from axillary draining lymphonodes(DLN) under the conditions of autologous deactivate tumor cells and low dose recombining interleukin-2 were performed. Cell expansion, T lymphocytes phenotype and special antitumor cytotoxic activity were analysed. More primary T lymphocytes subgroups can be getted from DLN than that of TIL. Furthermore, both the phenotype of lymphocyte and the special cytotoxic activity of DLN are similar to that of TIL. T lymphocytes in DLN can be used as a new source of effect cells for special adoptive immunotherapy to the neoplasm.
出处 《山东医科大学学报》 1996年第4期328-330,共3页 Acta Academiae Medicinae Shandong
关键词 腹腔镜术 脑室腹腔分流 脑积水 T Lymphocyte Lymphonode Axillary fossa Breast neoplasm Cell, cultural
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