摘要
目的探讨亚低温治疗对急性重症脑血管病患者预后的影响。方法将入选的61例患者随机分为亚低温组(31例)及对照组(30例),分析患者的临床资料。结果亚低温组并发全身炎症反应10例,衰竭器官数为51个,对照组治疗期间合并全身炎症反应16例,衰竭器官数为98个,两组患者出现全身炎症反应综合征及衰竭器官的数目差异有显著性意义;亚低温组2例死于脑干衰竭,2例死于多器官功能衰竭;对照组2例死于脑干衰竭,4例死于多器官功能衰竭,2例死于急性脑疝。病死率亚低温组12.9%(4/31);对照组26.7%(8/30),亚低温组明显低于对照组(P<0.01);1个月后随访,亚低温组患者神经功能恢复程度明显好于对照组,差异有显著性意义。结论亚低温治疗对急性重症脑血管病患者具有保护作用,能减少器官衰竭的数目,降低病死率,改善预后。
Objective To explore the influence of mild hypothermia on patients with acute severe cerebral stroke complicated by systemic inflammatory reaction（ SIR）/MOF. Methods Sixty-one cases were randomly divided into hypothermie group （ n = 31） and control group （ n = 30）. Their clinical data were analyzed. Resuits There were 10 eases complicated by SIR and 51 organs in failure in hypothermie group, while there were 16 eases complicated by SIR and 98 organs in failure in control group, with significant statistical difference between the 2 groups （ P 〈 0.01, P 〈 0.05）.Two eases died of brainstem failure and 2 eases died of MOF in hypothennie group;while in control group, 2 eases died of brainstem failure,4 cases died of MOF and 2 eases died of brain hernia.The fatality rates in mild hypothermie group and control group were 12.9% （4/31） and 26.7%（8/30） respectively（ P 〈 0.01）. After followed up for 1 month, the score of CSS was significantly higher in hypothermie group than in control group. Conclusions Mild hyperthermia has the protective effect against the acute severe cerebral stroke complicated by SIR/MOF. It can reduce the number of failed organs and fatality rate, and improve the prognosis.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2006年第7期465-467,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词
脑血管障碍
低温
脓毒症综合征
多器官功能衰竭
cerebrovascular disorders
hypothermia
sepsis syndrome
multiple organ failure
