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复发性腹膜后肿瘤综合治疗26例体会 被引量:2

Experience of complex treatment to 26 cases with recurrent retroperitoneal tumor
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摘要 目的:探讨复发性腹膜后肿瘤的综合治疗方法。方法:回顾分析1998年~2004年收治的26例复发性腹膜后肿瘤患者,经手术、放/化疗以及介入治疗的临床资料。结果:肿瘤全切除或扩大切除14例,部分切除或剖腹探查12例,全组无手术死亡,术后5年存活2例(7.7%),3年存活5例(19.2%),1年存活8例(30.8%),其余11例在1年内死亡。其中放/化疗20例,放疗剂量50~60Gy,化疗采用AC方案(阿霉素和环磷酰胺)。选择性动脉灌注5-Fu介入疗3例,I^125粒子组织间放射治疗3例。全切除或扩大切除术后肿瘤再复发9例(64.3%),再次手术4例。结论:以手术为主的综合治疗方法,能延长复发性腹膜后肿瘤患者的生存期,改善生活质量。 Objective:To probe the combined treatment to cases with recurrent retroperitoneal tumor. Methods:To retrospectively analysis the clinical data of 26 patients with recurrent retroperitoneal tumor admitted from 1998 to 2004, who had been undergone operation radio-chemotherapy or interventional treatment respectively. Results:In whole group, none of patients died during operation, 14 cases endured tumor resection totally or extensively, partial resection or exploratary laparotomy for 12 cases, 2 cases survived for 5 years after operation (7. 7% ) , 5 cases for 3 years( 19. 2% ), 8 cases for a year(30. 8% ) , 11 patients died within a year. In wich of all patients, 20 cases endured radio-chemotherapy, radiotherapeutic dose arrange from 50 to 60Gy and chemotherapeutic program with AC (Adriamycin and Cyclophosphamide), interventional treatment of selective arterioperfusion with 5-FU for 3 cases, intratissue radiotherapy with I^125 particle for 3 cases. 9 patients relapsed recurrent tumor after operation of tumor resection partially or extensively (64. 3% ), 4 cases endured secondary operation. Conclusion:Combined treatment leaded by operation can lengthen survival period of patients with recurrent retroperitoneal tumor and improve their quality of life.
出处 《临床肿瘤学杂志》 CAS 2006年第6期448-449,454,共3页 Chinese Clinical Oncology
关键词 腹膜后肿瘤 复发 外科 放疗 化疗 Retroperitoneal tumor Recurrence Surgery Radio theapy Chemotheapy
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  • 1Dalton RR, Donohue JH, Mucha P, et al. Management of retroperitoneal sarcomas. Surgery, 1989,106:725-733.
  • 2Jaques DP, Coit DG, Hajdu SI, et al. Management of primary and recurrent soft-tissue sarcoma of the retroperitoneum. Ann Surg, 1990, 212:51-59.
  • 3Lewis JJ, Leung D, Woodruf JM, et al. Retroperitoneal soft-tissue sarcoma: analysis of 500 patients treated and followed at a single institution. Ann Surg, 1998, 228:355-365.
  • 4陈方满,侯书法,张东生,芮景.介入治疗原发性腹膜后恶性肿瘤的临床价值[J].放射学实践,1999,14(3):150-151. 被引量:8

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