摘要
目的通过临床随机对照试验,比较浅-中-浅低温高钾氧合血与高钾氧合冷血对心肌保护的作用。方法将20例心脏瓣膜病患者,随机分成两组:采用自配含5%KCI的停跳液与氧合血按1∶50左右比例配成浅-中-浅低温高钾氧合血经冠状动脉顺行灌注(实验组),氧合血与St Thomas停搏液按4∶1混合成高钾氧合冷血经冠状动脉顺行灌注(对照组)。观察体外循环时间,升主动脉阻闭时间,自动复跳率、强心药使用时间、机械通气时间、ICU停留时间。结果两组在观察体外循环时间,升主动脉阻闭时间无差别(P>0.05),自动复跳率实验组明显高于对照组(P<0.05),强心药使用时间、机械通气时间I、CU停留时间方面,实验组明显低于对照组(P<0.05)。结论在心肌保护方面浅-中-浅低温高钾氧合血优于高钾氧合冷血。
Objective Through clinical randomized controlled trial, to compare effectiveness of shallow-midst-shallow hypothermy of hyperconcentrative kalium oxygenate blood with hyperconcentrative kalium oxygenate cold-blood on myocardial preservation. Methods Twenty cases with valvular disease of the heart were divided into two groups by random. Experiment group was antegrade perfused per aeteria coronaria using autogamia shallow-midst-shallow hypothermy hyperconcentrative kalium oxygenate blood （5% KCl stop skipping liquid：oxygenate blood or so 1 ： 50）. Controlled group was antegrade perfused per aeteria coronaria using hyperconcentrative kalium oxygenate cold-blood （St Thomas stop skipping liquid：oxygenate blood or so 1 ： 4）. Extracorporeal circulation time, ascending aorta blocked up time, automatic ambo-skip rate, cardiotonic using time, mechanical ventilation time, and ICU detention time were observed. Results No significant difference between two groups in cardiopulmonary bypass time and ascending aorta blocked up time（P〉 0. 05）;Experiment group surpasses control group in automatic ambo-skip rate（P〈0.05）;Experiment group was lower than control group in cardiotonic using time, mechanical ventilation time, and ICU detention time. Conclusion Shallow-midst-shallow hypothermy of hyperconcentrative kalium oxygenate blood surpasses high kalium oxygenate cold-blood in myocardial protection.
出处
《江西医学院学报》
2006年第3期83-84,87,共3页
Acta Academiae Medicinae Jiangxi
关键词
心肌保护
浅-中-浅模式
对比研究
myocardial protection, shallow-midst-shallow mode
control study
