摘要
目的:研究急性低频下降型感音神经性听力损失(ALHL)的病因、诊断和治疗方法。方法:选择55例ALHL患者为研究对象,经详细询问病史和耳专科检查后,行纯音测听,声导抗测听和听性脑干反应(ABR),随机分为泼尼松组和对照组治疗,疗程结束后随访6个月。结果:两组患者多以青年为主,主要症状为耳闷,低音调耳鸣和听力减退,耳科检查无殊。所有患者(55例58耳)纯音听阈示轻到中度低频感音神经性聋,鼓室导抗图“A”型,49耳镫骨肌反射引出,其中40耳Metz试验阳性。受检的45耳中ABR均正常。治疗后泼尼松组效果优于对照组(P<0.05)。结论:ALHL以突发的低音调耳鸣,听力减退和耳闷为主要表现,常单耳发病,听力学定位诊断提示为蜗性病变,仅累及低频区。本病对皮质类固醇激素有一定的治疗效果。
Objective：To study the etiology, diagnosis and therapeutic strategies of acute low-tone sensorineural hearing loss （ALHL）. Method： Fifty-five patients （58 ears） with ALHL were selected for this study. With detailed history collection, otological examination and pure tone audiometry,acoustic immittance and auditory brainstem response （ABR）, all cases were divided into two groups, the prednisone group and the control group, randomly with six months＇ follow-up. Result： ALHL mainly affected young people. The symptoms included the sensation of ear fullness, low-tone tinnitus, and hearing impairment. Otological examinations showed normal results. Mild to moderate sensorineural hearing loss at low frequencies and type ＂A＂ tympanograms were found in all cases. Acoustic stapedial reflexes were elicited in 49 out of 58 affected ears and 40 of them had positive results on the Metz test. ABR responses were normal in all 45 tested ears. with comparison of the two groups, the effect of prednisone group was superior to that of the control group. Conclusion： ALHL patients are clinically characterized by low-tone tinnitus, aural fullness and hearing loss, which mainly involve unilateral ear. Audiological findings indicate cochlear impairment, which only invades low frequency region. This study suggest that the corticosteroid therapy probably have some effect.
出处
《临床耳鼻咽喉科杂志》
CSCD
北大核心
2006年第13期602-604,共3页
Journal of Clinical Otorhinolaryngology
关键词
听力丧失
低频
糖皮质激素
Hearing loss,low-frequency
Glucocorticoids
