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颞叶癫痫术前评估的手术意义

The value of preoperative evaluation for temporal lobe surgery.
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摘要 目的对拟行手术的顽固性颞叶癫痫患者术前进行综合评估,明确致痫灶部位,实施个体化手术方案。方法对32例颞叶癫痫患者术前进行视频脑电图(V-EEG)、磁共振成像(MRI)、正电子发射断层扫描(PET)检查,综合分析检查结果,制定相应手术方案。术中行皮层脑电描记,术后对切除组织进行病理检查,并对患者进行手术后随访。结果V-EEG、MRI、PET3种检查定位结果完全一致的有21例。29例患者(90.6%)术后癫痫发作完全或部分缓解,3例患者(9.4%)无明显缓解。结论对顽固性颞叶癫痫患者术前进行综合评估,对制定合理的手术方案,提高治愈率有重要指导意义。 Objective We took a series of assessments and investigations on intractable temporal lobe epilepsy patients before surgery to make accurate localization and lateralization, and use different surgical strategies for different subtypes of patients. Methods Thirty-two patients with temporal lobe epilepsy were examined by Video-EEG, MRI, PET. After preoperative evaluation open cranioectomy was performed in all patients and the tissue resected was examined with pathological test. Results The results of Video-EEG, MRI, PET were coherent in twenty-one patients. 29 patients (90. 6%) had been completely or incompletely free of seizure since surgery and 3 cases(9. 4%) had no significant improvement. Conclusion: Preoperative evaluation can play an important role in making temporal lobe surgical strategies and help to promote the surgical outcome.
出处 《华中医学杂志》 CAS 2006年第3期165-166,共2页 Central China Medical Journal
关键词 颞叶癫痫 手术 术前评估 Temporal lobe epilepsy Surgery Preoperative evaluation
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参考文献4

  • 1Quarato PP,Gennaro GD,Mascia A et al.Temporal lobe epilepsy surgery:different surgical strategies after a non-invasive diagnostic protocol.J Neurol Neurosurg Psychiatry,2005,76:815
  • 2Wiebe S,Blume WT,Girvin JP et al.A randomized,controlled trial of surgery for temporal-lobe epilepsy.N Engl J Med,2001,345(5):311
  • 3Williamson PD,Thadani VM,French JA et al.Medial temporal lobe epilepsy:videotape analysis of objective clinical seizure characteristics.Epilepsia,1998,39(11):1182
  • 4Gilliam F,Faught E,Martin R et al.Predictive value of MRI-identified mesial temporal sclerosis for surgical outcome in temporal lobe epilepsy:an intent to treat analysis.Epilepsia,2000,41(8):963

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