摘要
五种四环类抗生素的固体表面荧光法的研究解宏智，董川，刘长松，赵丽霞，杜学勤（山西大学化学系，太原，０３０００６）关键词固体表面荧光，碱性降解，四环类抗生素四环类抗生素的亲癌作用使其成为诊断和治疗肿瘤的荧光探针［１］，基于该类抗生素碱性降解速率的差异［...
The solid surface room temperature fluorescence (SS-RTF)for determination of five tetracyclines on filter paper and the simultaneous determination of chlortetracycline(CTC)and tetracycline (TC) or CTC and oxytetracycline were described.Various factors of effect on RTF intensities of tetracyclines, such as pH condition, drying temperature and time of sample etc. were studied. The linear dynamic ranges, limit of detections and RSD were:2.1￣205.0ng,1.3ng and 3.1 % for CTC;5.9￣496.4ng,1.8ng and 2.6% for OTC;3.8￣481. 0 ng,3. 6 ng and 2.8 % for TC;3.7￣462.6ng,2. 7 ng and 4.1 % for doxycycline (DOTC); 5.8￣193.0ng,5. 2 ng and 3.4% for methacycline (MTC), respectively. The recoveries of them in urine are from 95 % to 105%.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1996年第8期1216-1218,共3页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
山西省自然科学基金
关键词
碱性降解
四环类
抗生素
固体表面荧光法
Solid surface room temperature flourescence, Alkaline degradation, Tetracyclines
