摘要
４－硝基邻苯二甲酸根桥联双核钴（Ⅱ）配合物的合成、磁性及抗癌活性石敬民，廖代正，程鹏，缪明明，姜宗慧，刘永江，王耕霖（南开大学化学系天津３０００７１）关键词硝基邻苯二甲酸根，双核钴（Ⅱ）配合物，磁性，生物活性研究桥联多核配合物的磁性不仅有助于了解桥联...
Two new novel binuclear cobalt (Ⅱ) complexes, namely,[Co_2 (4PT) (Phen)_4]( ClO_4 )_2· 3H_2O (complex 1) and[Co_2 (4PT)(NPhen)_4] (ClO_4)_2·2H_2O (complex 2) (4PT=4-nitrophthalato , Phen=l,10-phenanthroline , NPhen = 5-nitro-1,10-phenanthroline) have been synthesized. The complexes were characterized by elemental analysis, IR, UV-Vis spectra and electronic conductance. The variable-temperature magnetic susceptibility of the complexes was measured over 77￣300 K. The data were analyzed by using the magnetic susceptibility equation based on Heisenberg spin-exchange operator, and the exchange integrals for complex 1 and complex 2 were found 2J= - 8. 6 cm￣(-1) and 2J=-4. 3 cm￣(-1),respectively. Experiments of inhibiting human leukemia cell, stomach cancer cell and carcinoma of nasopharyngeal cancer cell in vitro were made,and found that the complexes exhibited a relatively strong function of inhibiting these three kinds of cancer cells.
出处
《应用化学》
CAS
CSCD
北大核心
1996年第4期86-88,共3页
Chinese Journal of Applied Chemistry
基金
国家自然科学基金
配位化学国家重点实验室资助
关键词
硝基
邻苯二甲酸
配合物
磁性
钴
抗癌活性
nitrophthalate
binuclear Co(Ⅱ) complex
magnetism
bioactivity
