期刊文献+

各年龄段成年人的高血压:当前社区人群的预后和控制

Hypertension in Adults Across the Age Spectrum: Current Outcomes and Control in the Community
暂未订购
导出
摘要 背景:对于80岁以上的人群,目前有关高血压的治疗和控制率以及高血压相关危险性的数据很少。目的:明确老年高血压患者各级别血压的患病率、高血压的治疗率和控制率以及心血管危险因素。设计、地点及参试者:社区队列研究,数据收集于20世纪90年代进入Framinghanl心脏研究的全部检查。根据年龄将入选者集中分层:60岁以下、60~79岁和〉t80岁。共5296例入选者,检查14458人次,其中高血压7135人次(治疗4919例)。主要观测指标:比较各年龄段人群高血压的患病率、治疗率和控制率。6年随访期间发生心血管疾病的危险性,采用Cox比例风险回归的多变量校正风险比(hazardratios,HRs)和95%可信区间(confidenceintervals,CIs)评估。结果:高血压的患病率和药物治疗率随着年龄增加而升高,但是在老年女性控制率(收缩压〈140mmHg,舒张压〈90mmHg)显著降低。〈60岁、60~79岁和t〉80岁组男性的控制率分别为38%、36%和38%(P=0.30);女性的控制率分别为38%、28%和23%(P〈0.001)。随着年龄增加,与血压分级升高相关的心血管疾病的相对危险性没有下降,而绝对危险性显著升高。在〉t80岁的参试者,正常血压组(对照组)主要心血管事件的发生率为9.5%,高血压前期、1级高血压以及2级或治疗的高血压组的发生率分别为19.8%(HR,1.9;95%CI,0.9~3.9)、20.3%(HR,1.8;95%CI,0.8~3.7)和24.7%(HR,2.4;95%CI,1.2~4.6)。结论:相对于目前的国家指南,在社区人群血压的控制率较低,特别是在老年女性高血压患者。短期心血管疾病危险性很高表明,对于老年高血压患者应加大安全有效降低危险性的力度。
出处 《美国医学会杂志(中文版)》 2006年第3期156-161,共6页 The Journal of the American Medical Association(Chinese Edition)
  • 相关文献

参考文献43

  • 1Meyer J. Age: 2000. Census 2000 Brief. Washington. DC: US Dept of Commerce. Economics and Statistics Administration. US Census Bureau; 2001.
  • 2Fields LE, Burr VL, Cutler JA, Hughes J, Roccella El.Sorlie P. The burden of adult hypertension in the United States 1999 to 2000: a rising tide. Hypertension. 2004;44:398-404.
  • 3Dahlof B, Lindholm LH, Hansson L, Schersten B,Ekbom T, Wester PO. Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension(STOP-Hypertension). Lancet. 1991 ;338:1281-1285.
  • 4Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension: final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA. 1991 ;265:3255-3264.
  • 5Gueyffier F, Bulpitt C, Boissel J-P, et al. Antihypertensive drugs in very old people: a subgroup meta-analysis of randomised controlled trials. Lancet. 1999;353:793-796.
  • 6Hansson L, Lindholm LH, Ekbom T, et al. Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study. Lancet. 1999;354:1751-1756.
  • 7Staessen JA, Fagard R, Thijs L, et al.Randomised double-blind companson of placebo and active treatment for older patients with isolated systolic hypertension. Lancet. 1997;350:757-764.
  • 8Liu L, Wang JG, Gong L, Liu G, Staessen JA. Comparison of active treatment and placebo in older Chinese patients with isolated systolic hypertension: Systolic Hypertension in China (Syst-China) Collaborative Group. J Hypertens. 1998;16:1823-1829.
  • 9Coope J, Warrender TS. Randomised trial of treatment of hypertension in elderly patients in primary care.BMJ. 1986;293:1145-1151.
  • 10Burt VL, Culter JA, Higgins M, et al. Trends in the prevalence, awareness, treatment, and control of hypertension in the adult US population: data from the health examination surveys, 1960 to 1991.Hypertension. 1995;26:60-69.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部