摘要
目的探讨静止性腔隙性脑梗死(SLI)老年患者认知功能障碍的特点。方法临床收集128名患者和38名对照者,根据MRI影像按照SLI梗死数的多少将患者进一步分为单个SLI组和多发SLI组,分别进行简明精神状态量表(MMSE)测验、积木测验和画钟测验。结果(1)单个SLI组患者的MMSE、积木测验和画钟测验评分与对照组相比无明显差异(P>0·05),而多发SLI组患者MMSE、积木测验和画钟测验评分较对照组显著降低(P<0·01);(2)与对照组相比,单个SLI组MMSE各分值评分均无显著降低(P>0·05),而多发SLI组MMSE时间定向、地点定向、短程记忆、注意力、计算力、图形描画分值评分显著降低(P<0·05)。结论多发SLI与认知功能下降密切相关,主要影响记忆、注意力、计算力和视空间、执行等认知功能。
Objective To investigate the characteristics of cognitive disorder in elderly patients with silent lacunar infarctions（SLI）. Methods 128 patients and 38 controls were admitted into our research. Patients were classified into single SLI group and multiple SLI group according to MRI. All patients and controls＇ cognitive status were assessed with MMSE, block-test, clock-drawing test. Results ① All scores of MMSE, block test and clock-drawing test in multiple SLI group were significantly lower than those in control group. There were no significant differences in scores of MMSE, block test and clock-drawing between single SLI group and control group. ② Compared with control group, the patients in multiple SLI group had lower scores in time orientation, place orientation, short-term memory, attention, calculation, visual-spatial function and executive function and so on. Conclusions Multiple SLI is closely related with cognitive functions.
出处
《实用老年医学》
CAS
2006年第3期179-181,共3页
Practical Geriatrics
关键词
脑梗塞
认知障碍
老年人
Brain infarction
Cognition disorders
Aged
